Medicines are occasionally prescribed for functions other than These detailed in a very Affected person Info leaflet. Tend not to use VIAGRA to get a problem for which it wasn't prescribed. Tend not to give VIAGRA to Others, although they've got the same indicators that you've got. It might hurt them.

This metabolite includes a PDE selectivity profile just like sildenafil and an in vitro potency for PDE5 close to fifty% from the dad or mum drug. Plasma concentrations of the metabolite are close to forty% of Individuals seen for sildenafil, so that the metabolite accounts for about 20% of sildenafil's pharmacologic results.

Tatt i betraktning at around 20 millioner menn bruker sildenafil citrate årlig, er risikoen for potensielle bivirkninger ytterst liten. Ytterligere informasjon om bivirkninger finnes i preparatets pakningsvedlegg. Skulle du oppleve bivirkninger som blir plagsomme eller som ikke er beskrevet her, anbefales det at du slutter å bruke medisinen umiddelbart og kontakter lege eller apotek for råd. Dette gjelder også dersom du får en ereksjon som varer mer enn 4 timer. Forholdsregler ved kjøp av Viagra

The first indication of sildenafil is therapy of erectile dysfunction (incapacity to maintain a satisfactory erection to finish sexual intercourse). Its use is now one of many regular therapies for erectile dysfunction, including for males with diabetic issues mellitus.[eighteen]

Hvis du er allergisk for noen av de aktive ingrediensene Når du tar potensstyrkende piller, skal du sørge for at du ikke tar medisiner som du ikke har nevnt i din on the web konsultasjon eller nevnt til din lege. Det er viktig å nevne både kosttilskudd, reseptfrie og reseptbelagte get more info medisiner til legen for å utelukke uheldige interaksjoner.

The usage of sildenafil and an α1 blocker (usually prescribed for hypertension or for urologic disorders, such as benign prostatic hypertrophy) at the same time may well bring about low hypertension, but this impact won't take place Should they be taken at the very least four hrs apart.[29]

Twenty subjects obtained VIAGRA fifty mg, but only 19 subjects received matching placebo. 1 client discontinued the research prematurely due to an adverse party of hypotension pursuing dosing with VIAGRA fifty mg. This client were using minoxidil, a strong vasodilator, through the review.

It truly is eliminated predominantly by hepatic metabolism (primarily CYP3A4) and is transformed to an active metabolite with Houses much like the father or mother, sildenafil. Each sildenafil and the metabolite have terminal fifty percent life of about 4 hrs.

Continue to keep sildenafil out with the attain of kids. If you retain sildenafil oral liquid in a refrigerator, Ensure that you retain it clear of children who also use the fridge.

All through 2012 Viagra shed its posture as the highest offering erectile dysfunction therapy in South Korea. This development was credited mostly "mainly because of the introduction of generic solutions." Generic sildenafil became publicly readily available in Might.

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PDE3 is concerned in charge of cardiac contractility. Sildenafil is just about 10-fold as strong for PDE5 compared to PDE6, an enzyme located in the retina that's involved in the phototransduction pathway of your retina. This lessen selectivity is regarded as the basis for abnormalities relevant to shade vision [see Pharmacodynamics].

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